PetMedix raises $37M Series B

PetMedix™ announces today the completion of an oversubscribed $37M (£27M) Series B financing
round that will be used to advance its innovative pipeline through clinical development. The
investment brings two new investors into PetMedix: global technology company Tencent and
Japanese corporation Kyoritsu Holdings alongside strong continued support from U.S.-based
investor Digitalis Ventures, and British funds Parkwalk Advisors and Cambridge Innovation Capital.
This investment enables PetMedix to take its next step towards becoming a truly global animal
health company, and the first to bring fully species-specific therapeutic antibodies to veterinary
medicine. The £27M raised represents a first close of the series B and PetMedix is open to engaging
with suitable investors interested in extending the round.

“PetMedix has a global vision: elevating expectations in pet care the world over. This financing round
not only provides the capital required to take us to the next level, but also the international
perspective to help us meet our goals,” says Tom Weaver, PhD, PetMedix CEO and co-founder.

This financing round will propel PetMedix from an R&D-stage, UK-focused biotech company, into a
clinical-stage international organisation. PetMedix’s internal discovery programmes will continue to
advance through development on their way to regulatory approval. While the initial focus will be the
United States, the company has built an international organisation and financing syndicate to support
efforts in European and Asian markets as well.

PetMedix was spun out the lab of Prof Allan Bradley FRS in 2018, based on the PhD work of his student,
now PetMedix co-founder, Jolyon Martin. At the time, there was a nascent version of the Ky9™
transgenic platform, and no team, premises, or pipeline to speak of. In the two and a half years that
followed, PetMedix has established itself as a leader in the emerging companion animal antibody field
and is currently the only group capable of making mature, fully species-specific antibodies.

Along the way, PetMedix has expanded operations in state-of-the-art facilities, grown the team to
more than 40 world leading scientists, and secured a partnership deal with Boehringer Ingelheim
Animal Health. It is the scientific achievements, however, that have set PetMedix apart. The recent
completion of the Ky9 platform marks the single largest transfer of DNA from one species to another,
not involving human DNA, as to date PetMedix scientists have engineered 5.5 Mbp of dog and cat
genomic sequence into the Ky9 and Felyne™ platforms respectively.

The Ky9 platform alone has so far generated more than 50,000 fully canine, antigen-specific
antibodies. This depth and diversity of target-specific antibodies allows PetMedix scientists to be
meticulous in every step of the discovery pipeline, ensuring only the highest-quality therapeutic
candidates advance into the clinic.

“It is comparatively easy these days to make an antibody; it remains very difficult to make a
therapeutic quality antibody that can make it all the way to being an approved drug,” explains Dr Dave
Lowery, PetMedix’s Chief Product Development Officer.

This sentiment is imbued in every step of PetMedix’s drug discovery pathway. From the way the
platform is designed to the criteria used for candidate screening and selection, everything is optimised
to maximise the chances of yielding affordable, effective, and safe therapeutics that make it all the
way to the hands of a vet as a licensed medicine. This diligence and care are yielding their first signs
of success, as candidate antibodies from an internal PetMedix program recently completed a canine
study and outperformed all relevant benchmarks.

“It’s an exciting time for PetMedix,” Dr Weaver says. “We’ve delivered on all of our Series A goals by
building this incredible team, putting together this unrivalled drug discovery engine, and getting
multiple internal programs underway. We are now focusing on clinical development on the path to
regulatory approval, and ultimately to bringing much-needed innovative therapies to companion
animals.”

Alastair Kilgour, CIO at Parkwalk Advisors, who co-led the funding round with Digitalis, said: “The past
18 months have amply highlighted the importance and impact of investing in the companies behind
the development of innovative breakthroughs in human medicine, but much less well understood is
the need to do the same for veterinary medicine to improve health outcomes for pets and other
animals. PetMedix has made incredible progress in this field over the past few years – developing a
platform to create canine- and feline-specific antibodies to treat various diseases and illnesses.
Parkwalk is proud to have backed the team from the start, and to be doubling down on that backing
in this latest round, and we look forward to watching them continue to innovate and grow through
this exciting next phase for the business.”